By Arthur M. Silverstein
Written by means of an immunologist, A background of Immunology traces the concept that of immunity from precedent days as much as the current day, analyzing how altering ideas and applied sciences have affected the process the technological know-how. It indicates how the personalities of scientists or even political and social components motivated either idea and perform within the box. With interesting tales of clinical disputes and transferring medical developments, each one bankruptcy examines an enormous side of this self-discipline that has been so significant to the advance of contemporary biomedicine. With its biographical dictionary of vital scientists and its lists of important discoveries and books, this quantity will give you the such a lot whole historic reference within the field.
- Written in a chic variety via long-time working towards immunologist
- Discusses the altering theories and applied sciences that guided the field
- Tells of the fascinating disputes between well-known scientists
- Lists all of the vital discoveries and books within the field
- Explains intimately the numerous Nobel prize-winning contributions of immunologists
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Extra resources for A History of Immunology, Second Edition
Species and Specificity: An Interpretation of the History of Immunology, Cambridge, Cambridge University Press, 1995. 52. , Centralbl. Klin. Med. 9:681, 1888. 53. , Berl. Klin. Wochenschr. 37:615, 1900. 54. , Deutsch. Med. Wochenschr. 16:1145, 1890. , Virchow’s Arch. 84:87, 1881. one of Metchnikoff’s most suggestive biological romances... George Bernard Shaw, The Doctor’s Dilemma In a major address to the congress of the British Medical Association in 1896, Lord Lister suggested that if ever there had been a romantic chapter in the history of pathology, it was certainly that concerned with theories of immunity.
49 In studies of anthrax infection of Algerian sheep, Chauveau observed that the offspring of ewes infected during pregnancy, and especially shortly before parturition, showed an increased resistance to anthrax infection. Chauveau suggested that this increased immunity was due to the retention of inhibitory substances within the body of the infected mother, and their transmission across the placenta to the fetus in utero. Little more was heard of the retention theory following the discovery of antitoxic and other antibacterial antibodies in the early 1890s.
Being still much involved in elaborations of his side-chain receptor theory of antibody formation, he suggested that both bacteria and tumor cells might possess specific ‘‘chemoreceptors’’ which enable them to bind and then ingest those nutrients necessary to their growth. Ehrlich suggested that Pasteur need not have insisted upon complete depletion of a vital nutrient in the host – this he thought improbable – but that it may suffice that either the nutrient is reduced below a critical level, or more possibly that the pathogen has lost the ability (receptors) to utilize that nutrient – a sort of atrophy of specific receptors!