Download Creatine and Creatine Phosphate: Scientific and Clinical by Michael A. Conway (Author), Joseph F. Clark (Author) PDF

By Michael A. Conway (Author), Joseph F. Clark (Author)

Creatine and Creatine Phosphate: medical and scientific views is an up to date precis of either the clinical and scientific facets of creatine and creatine phosphate metabolism and therapy.It covers intimately the elemental biochemistry, bioenergetics and biophysics of those brokers with specific emphasis on their function at the cardiovascular and muscle structures. smooth in vivo myocardial and skeletal muscle measurements are defined, and the significance of the molecules in cardiovascular medication, game technology and cardiac surgical procedure are highlighted.This booklet is designed for these drawn to the fundamental medical historical past to creatine and creatine phosphate, and likewise for physicians treating or learning center and vascular disorder. The booklet may also be very important for activities scientists who desire to gather a finished wisdom of the molecule that's at the moment being promoted for functionality and workout programmes.

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Extra info for Creatine and Creatine Phosphate: Scientific and Clinical Perspectives

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6. Introduction NMR studies of ATP and creatine phosphate in the heart Creatine phosphate metabolism investigated with fl-guanidinopropionic acid Creatine phosphate in skeletal muscle Creatine transport Summary References 33 34 36 39 41 46 46 Key words: heart, artery, creatine kinase, skeletal muscle 1. INTRODUCTION Creatine (Cr) and creatine phosphate (PCr) metabolism have been studied by numerous groups over the past 20 years. In this chapter we present a brief summary of the current understanding of PCr metabolism using 31p N M R analysis in experimental preparations of heart, skeletal and smooth muscle as well as cell culture techniques for measuring creatine transport.

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20, 465-479. S. V. (1991). Discrete subcellular localization of a cytoplasmic and a mitochondrial isozyme of creatine kinase in intestinal epithelial cells. Cell Motil. Cytoskeleton 19, 169-179. K. B. (1993). Functional coupling between sarcoplasmicreticulum-bound creatine kinase and Ca-ATPase. Eur. J. Biochem. 213, 973-980. EM. E (1989). Creatine kinase isozyme expression in embryonic chicken hearts. Anat. Embryol. 179, 387-393. G. N. (1977). Functional coupling between Ca-ATPase and creatine phosphokinase in sarcoplasmic reticulum of myocardium.

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